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BMCBI
2007
144views more  BMCBI 2007»
14 years 9 months ago
Accelerated search for biomolecular network models to interpret high-throughput experimental data
Background: The functions of human cells are carried out by biomolecular networks, which include proteins, genes, and regulatory sites within DNA that encode and control protein e...
Suman Datta, Bahrad A. Sokhansanj
GECCO
2007
Springer
256views Optimization» more  GECCO 2007»
15 years 3 months ago
A particle swarm optimization approach for estimating parameter confidence regions
Point estimates of the parameters in real world models convey valuable information about the actual system. However, parameter comparisons and/or statistical inference requires de...
Praveen Koduru, Stephen Welch, Sanjoy Das
BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
14 years 9 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...