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» Fixed-Parameter Algorithms in Phylogenetics
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82
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TCBB
2008
107views more  TCBB 2008»
14 years 10 months ago
Progressive Tree Neighborhood Applied to the Maximum Parsimony Problem
Abstract-- The Maximum Parsimony problem aims at reconstructing a phylogenetic tree from DNA sequences while minimizing the number of genetic transformations. To solve this NP-comp...
Adrien Goëffon, Jean-Michel Richer, Jin-Kao H...
NAR
2000
120views more  NAR 2000»
14 years 10 months ago
WIT: integrated system for high-throughput genome sequence analysis and metabolic reconstruction
The WIT (What Is There) (http://wit.mcs.anl.gov/WIT2/ ) system has been designed to support comparative analysis of sequenced genomes and to generate metabolic reconstructions bas...
Ross A. Overbeek, Niels Larsen, Gordon D. Pusch, M...
83
Voted
BMCBI
2008
145views more  BMCBI 2008»
14 years 10 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
GECCO
2003
Springer
189views Optimization» more  GECCO 2003»
15 years 3 months ago
A Forest Representation for Evolutionary Algorithms Applied to Network Design
Abstract. Network design involves several areas of engineering and science. Computer networks, electrical circuits, transportation problems, and phylogenetic trees are some example...
Alexandre C. B. Delbem, André Carlos Ponce ...
110
Voted
BMCBI
2005
132views more  BMCBI 2005»
14 years 10 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer