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VISSYM
2003
14 years 10 months ago
Visual Hierarchical Dimension Reduction for Exploration of High Dimensional Datasets
Traditional visualization techniques for multidimensional data sets, such as parallel coordinates, glyphs, and scatterplot matrices, do not scale well to high numbers of dimension...
Jing Yang, Matthew O. Ward, Elke A. Rundensteiner,...
BMCBI
2008
90views more  BMCBI 2008»
14 years 9 months ago
Genome-scale study of the importance of binding site context for transcription factor binding and gene regulation
Background: The rate of mRNA transcription is controlled by transcription factors that bind to specific DNA motifs in promoter regions upstream of protein coding genes. Recent res...
Jakub Orzechowski Westholm, Feifei Xu, Hans Ronne,...
BMCBI
2010
201views more  BMCBI 2010»
14 years 9 months ago
Analysis of X-ray Structures of Matrix Metalloproteinases via Chaotic Map Clustering
Background: Matrix metalloproteinases (MMPs) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-...
Ilenia Giangreco, Orazio Nicolotti, Angelo Carotti...
BMCBI
2007
265views more  BMCBI 2007»
14 years 9 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
BMCBI
2008
108views more  BMCBI 2008»
14 years 9 months ago
An analysis of the positional distribution of DNA motifs in promoter regions and its biological relevance
Background: Motif finding algorithms have developed in their ability to use computationally efficient methods to detect patterns in biological sequences. However the posterior cla...
Ana C. Casimiro, Susana Vinga, Ana T. Freitas, Arl...