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ACMSE
2007
ACM
15 years 3 months ago
Finding association rules of cis-regulatory elements involved in alternative splicing
Alternative splicing (AS) is a major mechanism to generate protein diversity. A single gene might generate hundreds or even thousands of different proteins. Recently, powerful lar...
Jihye Kim, Sihui Zhao, Steffen Heber
TCBB
2008
103views more  TCBB 2008»
14 years 11 months ago
DNA Motif Representation with Nucleotide Dependency
The problem of discovering novel motifs of binding sites is important to the understanding of gene regulatory networks. Motifs are generally represented by matrices (PWM or PSSM) o...
Francis Y. L. Chin, Henry C. M. Leung
IMSCCS
2006
IEEE
15 years 5 months ago
Frequency Distribution of TATA Box and Extension Sequences on Human Promoters
Background: TATA box is one of the most important transcription factor binding sites. But the exact sequences of TATA box are still not very clear. Results: In this study, we cond...
Wei Shi, Wanlei Zhou
GECCO
2005
Springer
140views Optimization» more  GECCO 2005»
15 years 5 months ago
MDGA: motif discovery using a genetic algorithm
Computationally identifying transcription factor binding sites in the promoter regions of genes is an important problem in computational biology and has been under intensive resea...
Dongsheng Che, Yinglei Song, Khaled Rasheed
IEEEPACT
2009
IEEE
15 years 6 months ago
DDCache: Decoupled and Delegable Cache Data and Metadata
Abstract—In order to harness the full compute power of manycore processors, future designs must focus on effective utilization of on-chip cache and bandwidth resources. In this p...
Hemayet Hossain, Sandhya Dwarkadas, Michael C. Hua...