A complete understanding of transcriptional regulatory processes in the cell requires identification of transcription factor binding sites on a genomewide scale. Unfortunately, th...
We have previously proposed PTIDES (Programming Temporally Integrated Distributed Embedded Systems), a discrete-event framework that binds realtime with model time at sensors, act...
In this paper, we introduce the concept of metavariability, i.e., variability with respect to basic variability attributes like binding time or constraints. While the main focus o...
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
: The tumour suppressor protein p53 protein has a core domain that binds DNA and is the site for most oncogenic mutations. This domain is quite unstable compared to its homologs p...
Arumugam Madhumalar, Derek John Smith, Chandra Ver...