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BMCBI
2007
130views more  BMCBI 2007»
14 years 10 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
83
Voted
BMCBI
2005
124views more  BMCBI 2005»
14 years 10 months ago
Internet-based profiler system as integrative framework to support translational research
Background: Translational research requires taking basic science observations and developing them into clinically useful tests and therapeutics. We have developed a process to dev...
Robert Kim, Francesca Demichelis, Jeffery Tang, Al...
77
Voted
BMCBI
2005
118views more  BMCBI 2005»
14 years 10 months ago
Vestige: Maximum likelihood phylogenetic footprinting
Background: Phylogenetic footprinting is the identification of functional regions of DNA by their evolutionary conservation. This is achieved by comparing orthologous regions from...
Matthew J. Wakefield, Peter Maxwell, Gavin A. Hutt...
POPL
2012
ACM
13 years 5 months ago
Programming with binders and indexed data-types
We show how to combine a general purpose type system for an existing language with support for programming with binders and contexts by refining the type system of ML with a rest...
Andrew Cave, Brigitte Pientka
79
Voted
GPC
2009
Springer
15 years 2 months ago
G2G: A Meta-Grid Framework for the Convergence of P2P and Grids
Grid systems integrate distributed resources to form self-organization and self-management autonomies. Recently, for large-scale computation requirement, the collaboration of diffe...
Wu-Chun Chung, Chin-Jung Hsu, Yi-Shiang Lin, Kuan-...