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» Framework for a Protein Ontology
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BMCBI
2010
153views more  BMCBI 2010»
15 years 17 days ago
Analysis of substructural variation in families of enzymatic proteins with applications to protein function prediction
Background: Structural variations caused by a wide range of physico-chemical and biological sources directly influence the function of a protein. For enzymatic proteins, the struc...
Drew H. Bryant, Mark Moll, Brian Y. Chen, Viachesl...
95
Voted
COLING
2010
14 years 7 months ago
Dependency-Driven Feature-based Learning for Extracting Protein-Protein Interactions from Biomedical Text
Recent kernel-based PPI extraction systems achieve promising performance because of their capability to capture structural syntactic information, but at the expense of computation...
Bing Liu, Longhua Qian, Hongling Wang, Guodong Zho...
88
Voted
NAR
2006
74views more  NAR 2006»
15 years 12 days ago
NOPdb: Nucleolar Proteome Database
The Nucleolar Proteome Database (NOPdb) archives data on .700 proteins that were identified by multiple mass spectrometry (MS) analyses from highly purified preparations of human ...
Anthony Kar Lun Leung, Laura Trinkle-Mulcahy, Yun ...
95
Voted
BMCBI
2005
116views more  BMCBI 2005»
15 years 11 days ago
Dynamic covariation between gene expression and proteome characteristics
Background: Cells react to changing intra- and extracellular signals by dynamically modulating complex biochemical networks. Cellular responses to extracellular signals lead to ch...
Mansour Taghavi Azar Sharabiani, Markku Siermala, ...
83
Voted
BMCBI
2006
137views more  BMCBI 2006»
15 years 15 days ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...