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BMCBI
2006
131views more  BMCBI 2006»
15 years 4 months ago
The statistics of identifying differentially expressed genes in Expresso and TM4: a comparison
Background: Analysis of DNA microarray data takes as input spot intensity measurements from scanner software and returns differential expression of genes between two conditions, t...
Allan A. Sioson, Shrinivasrao P. Mane, Pinghua Li,...
BMCBI
2006
190views more  BMCBI 2006»
15 years 4 months ago
SNPs3D: Candidate gene and SNP selection for association studies
Background: The relationship between disease susceptibility and genetic variation is complex, and many different types of data are relevant. We describe a web resource and databas...
Peng Yue, Eugene Melamud, John Moult
BMCBI
2006
161views more  BMCBI 2006»
15 years 4 months ago
A novel approach to phylogenetic tree construction using stochastic optimization and clustering
Background: The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational bi...
Ling Qin, Yixin Chen, Yi Pan, Ling Chen
BMCBI
2006
202views more  BMCBI 2006»
15 years 4 months ago
DWARF - a data warehouse system for analyzing protein families
Background: The emerging field of integrative bioinformatics provides the tools to organize and systematically analyze vast amounts of highly diverse biological data and thus allo...
Markus Fischer, Quan K. Thai, Melanie Grieb, J&uum...
BMCBI
2006
60views more  BMCBI 2006»
15 years 4 months ago
Use of a multi-way method to analyze the amino acid composition of a conserved group of orthologous proteins in prokaryotes
Background: Amino acids in proteins are not used equally. Some of the differences in the amino acid composition of proteins are between species (mainly due to nucleotide compositi...
Alberto Pasamontes, Santiago Garcia-Vallvé
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