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136
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BMCBI
2008
15 years 3 months ago
2008
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
125
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BMCBI
2008
2008
Relating gene expression data on two-component systems to functional annotations in Escherichia coli
15 years 3 months ago
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...
150
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BMCBI
2010
15 years 3 months ago
2010
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
140
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BMCBI
2010
15 years 3 months ago
2010
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
143
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BMCBI
2007
15 years 3 months ago
2007
Background: Accurate sequence alignments are essential for homology searches and for building three-dimensional structural models of proteins. Since structure is better conserved ...