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BMCBI
2008
126views more  BMCBI 2008»
14 years 12 months ago
Combining Shapley value and statistics to the analysis of gene expression data in children exposed to air pollution
Background: In gene expression analysis, statistical tests for differential gene expression provide lists of candidate genes having, individually, a sufficiently low p-value. Howe...
Stefano Moretti, Danitsja van Leeuwen, Hans Gmuend...
BMCBI
2008
106views more  BMCBI 2008»
14 years 12 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
BMCBI
2006
102views more  BMCBI 2006»
14 years 12 months ago
SNA - a toolbox for the stoichiometric analysis of metabolic networks
Background: Despite recent algorithmic and conceptual progress, the stoichiometric network analysis of large metabolic models remains a computationally challenging problem. Result...
Robert Urbanczik
BMCBI
2007
128views more  BMCBI 2007»
14 years 12 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
CORR
2007
Springer
122views Education» more  CORR 2007»
14 years 11 months ago
Social Media as Windows on the Social Life of the Mind
This is a programmatic paper, marking out two directions in which the study of social media can contribute to broader problems of social science: understanding cultural evolution ...
Cosma Rohilla Shalizi
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