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BMCBI
2010
113views more  BMCBI 2010»
15 years 1 months ago
A classification model for distinguishing copy number variants from cancer-related alterations
Background: Both somatic copy number alterations (CNAs) and germline copy number variants (CNVs) that are prevalent in healthy individuals can appear as recurrent changes in compa...
Irina Ostrovnaya, Gouri Nanjangud, Adam B. Olshen
VCBM
2010
14 years 8 months ago
A General Approach to Model Biomedical Data from 3D Unorganised Point Clouds with Medial Scaffolds
We present the latest developments in modeling 3D biomedical data via the Medial Scaffold (MS), a 3D acyclic oriented graph representation of the Medial Axis (MA) [LK07, SP08]. Th...
Frederic F. Leymarie, Ming-Ching Chang, Celina Imi...
ICASSP
2011
IEEE
14 years 5 months ago
A stochastic compartmental approach to modeling and simulation of cancer spheroid formation and evolution
In this paper we model and simulate a biological system describing the evolution of cancer stem cells into tumors. Starting from some basic hypotheses about the behavior of these ...
Mónica F. Bugallo, Shishir Dash, Galina Bot...
ICST
2009
IEEE
15 years 8 months ago
Predicting Attack-prone Components
GEGICK, MICHAEL CHARLES. Predicting Attack-prone Components with Source Code Static Analyzers. (Under the direction of Laurie Williams). No single vulnerability detection techniqu...
Michael Gegick, Pete Rotella, Laurie A. Williams
RECOMB
2007
Springer
16 years 1 months ago
Association Mapping of Complex Diseases with Ancestral Recombination Graphs: Models and Efficient Algorithms
Association, or LD (linkage disequilibrium), mapping is an intensely-studied approach to gene mapping (genome-wide or in candidate regions) that is widely hoped to be able to effic...
Yufeng Wu