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» From Sequence to Biology: The Impact on Bioinformatics
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WABI
2004
Springer
15 years 5 months ago
A Polynomial-Time Algorithm for the Matching of Crossing Contact-Map Patterns
Abstract. Contact maps are a model to capture the core information in the structure of biological molecules, e.g., proteins. A contact map consists of an ordered set ¡ of elements...
Jens Gramm
89
Voted
ISMB
2007
15 years 2 months ago
Computational prediction of host-pathogen protein-protein interactions
Our major effort in this reporting period comprised functional genomic studies of key genes for carbon metabolite and nodulation/nitrogen fixation in Sinorhizobium meliloti, compar...
Matthew D. Dyer, T. M. Murali, Bruno W. S. Sobral
BMCBI
2010
138views more  BMCBI 2010»
14 years 11 months ago
A database and API for variation, dense genotyping and resequencing data
Background: Advances in sequencing and genotyping technologies are leading to the widespread availability of multi-species variation data, dense genotype data and large-scale rese...
Daniel Rios, William M. McLaren, Yuan Chen, Ewan B...
81
Voted
BMCBI
2007
154views more  BMCBI 2007»
14 years 11 months ago
Bounds on the distribution of the number of gaps when circles and lines are covered by fragments: Theory and practical applicati
Background: The question of how a circle or line segment becomes covered when random arcs are marked off has arisen repeatedly in bioinformatics. The number of uncovered gaps is o...
John Moriarty, Julian R. Marchesi, Anthony Metcalf...
BMCBI
2011
14 years 3 months ago
Faster Smith-Waterman database searches with inter-sequence SIMD parallelisation
Background: The Smith-Waterman algorithm for local sequence alignment is more sensitive than heuristic methods for database searching, but also more time-consuming. The fastest ap...
Torbjørn Rognes