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    BMCBI
    2008
    132views more  BMCBI 2008»
    Mixture models for analysis of melting temperature data
    14 years 12 months ago
    Mixture models for analysis of melting temperature data
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    Background: In addition to their use in detecting undesired real-time PCR products, melting temperatures are useful for detecting variations in the desired target sequences. Metho...
    Christoffer Nellåker, Fredrik Uhrzander, Joa...
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    BMCBI
    2008
    107views more  BMCBI 2008»
    Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
    14 years 12 months ago
    Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
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    Background: MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normaliz...
    Juan R. González, Josep L. Carrasco, Llu&ia...
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    BMCBI
    2008
    148views more  BMCBI 2008»
    Critical assessment of alignment procedures for LC-MS proteomics and metabolomics measurements
    14 years 12 months ago
    Critical assessment of alignment procedures for LC-MS proteomics and metabolomics measurements
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    Background: Liquid chromatography coupled to mass spectrometry (LC-MS) has become a prominent tool for the analysis of complex proteomics and metabolomics samples. In many applica...
    Eva Lange, Ralf Tautenhahn, Steffen Neumann, Cleme...
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    BMCBI
    2008
    123views more  BMCBI 2008»
    Validation of protein models by a neural network approach
    14 years 12 months ago
    Validation of protein models by a neural network approach
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    Background: The development and improvement of reliable computational methods designed to evaluate the quality of protein models is relevant in the context of protein structure re...
    Paolo Mereghetti, Maria Luisa Ganadu, Elena Papale...
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    BMCBI
    2008
    88views more  BMCBI 2008»
    Microarray-based gene set analysis: a comparison of current methods
    14 years 12 months ago
    Microarray-based gene set analysis: a comparison of current methods
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    Background: The analysis of gene sets has become a popular topic in recent times, with researchers attempting to improve the interpretability and reproducibility of their microarr...
    Sarah Song, Michael A. Black
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