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BMCBI
2004
150views more  BMCBI 2004»
14 years 11 months ago
Graph-based iterative Group Analysis enhances microarray interpretation
Background: One of the most time-consuming tasks after performing a gene expression experiment is the biological interpretation of the results by identifying physiologically impor...
Rainer Breitling, Anna Amtmann, Pawel Herzyk
BMCBI
2004
135views more  BMCBI 2004»
14 years 11 months ago
Determination of the differentially expressed genes in microarray experiments using local FDR
Background: Thousands of genes in a genomewide data set are tested against some null hypothesis, for detecting differentially expressed genes in microarray experiments. The expect...
Julie Aubert, Avner Bar-Hen, Jean-Jacques Daudin, ...
BMCBI
2004
176views more  BMCBI 2004»
14 years 11 months ago
Boosting accuracy of automated classification of fluorescence microscope images for location proteomics
Background: Detailed knowledge of the subcellular location of each expressed protein is critical to a full understanding of its function. Fluorescence microscopy, in combination w...
Kai Huang, Robert F. Murphy
BMCBI
2004
124views more  BMCBI 2004»
14 years 11 months ago
Tests for finding complex patterns of differential expression in cancers: towards individualized medicine
Background: Microarray studies in cancer compare expression levels between two or more sample groups on thousands of genes. Data analysis follows a population-level approach (e.g....
James Lyons-Weiler, Satish Patel, Michael J. Becic...
BMCBI
2004
169views more  BMCBI 2004»
14 years 11 months ago
A power law global error model for the identification of differentially expressed genes in microarray data
Background: High-density oligonucleotide microarray technology enables the discovery of genes that are transcriptionally modulated in different biological samples due to physiolog...
Norman Pavelka, Mattia Pelizzola, Caterina Vizzard...
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