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» Functional characterization and topological modularity of mo...
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BMCBI
2005
97views more  BMCBI 2005»
14 years 9 months ago
The yeast kinome displays scale free topology with functional hub clusters
Background: The availability of interaction databases provides an opportunity for researchers to utilize immense amounts of data exclusively in silico. Recently there has been an ...
Robin E. C. Lee, Lynn A. Megeney
BMCBI
2008
78views more  BMCBI 2008»
14 years 9 months ago
Deducing topology of protein-protein interaction networks from experimentally measured sub-networks
Background: Protein-protein interaction networks are commonly sampled using yeast two hybrid approaches. However, whether topological information reaped from these experimentallym...
Ling Yang, Thomas M. Vondriska, Zhangang Han, W. R...
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CANDC
2006
ACM
14 years 9 months ago
Identification of functional modules in a PPI network by clique percolation clustering
Large-scale experiments and data integration have provided the opportunity to systematically analyze and comprehensively understand the topology of biological networks and biochem...
Shi-Hua Zhang, Xue-Mei Ning, Xiang-Sun Zhang
BMCBI
2006
120views more  BMCBI 2006»
14 years 9 months ago
SCOWLP: a web-based database for detailed characterization and visualization of protein interfaces
Background: Currently there is a strong need for methods that help to obtain an accurate description of protein interfaces in order to be able to understand the principles that go...
Joan Teyra, Andreas Doms, Michael Schroeder, M. Te...
BMCBI
2007
202views more  BMCBI 2007»
14 years 9 months ago
ProtNet: a tool for stochastic simulations of protein interaction networks dynamics
Background: Protein interactions support cell organization and mediate its response to any specific stimulus. Recent technological advances have produced large data-sets that aim ...
Massimo Bernaschi, Filippo Castiglione, Alessandra...