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» Functional discrimination of membrane proteins using machine...
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BMCBI
2006
100views more  BMCBI 2006»
14 years 9 months ago
STAR: predicting recombination sites from amino acid sequence
Background: Designing novel proteins with site-directed recombination has enormous prospects. By locating effective recombination sites for swapping sequence parts, the probabilit...
Denis C. Bauer, Mikael Bodén, Ricarda Thier...
ICML
2007
IEEE
15 years 10 months ago
Classifying matrices with a spectral regularization
We propose a method for the classification of matrices. We use a linear classifier with a novel regularization scheme based on the spectral 1-norm of its coefficient matrix. The s...
Ryota Tomioka, Kazuyuki Aihara
BMCBI
2005
189views more  BMCBI 2005»
14 years 9 months ago
A sentence sliding window approach to extract protein annotations from biomedical articles
Background: Within the emerging field of text mining and statistical natural language processing (NLP) applied to biomedical articles, a broad variety of techniques have been deve...
Martin Krallinger, Maria Padron, Alfonso Valencia
BMCBI
2006
112views more  BMCBI 2006»
14 years 9 months ago
Protein disorder prediction by condensed PSSM considering propensity for order or disorder
Background: More and more disordered regions have been discovered in protein sequences, and many of them are found to be functionally significant. Previous studies reveal that dis...
Chung-Tsai Su, Chien-Yu Chen, Yu-Yen Ou
BMCBI
2008
143views more  BMCBI 2008»
14 years 9 months ago
Automatic detection of exonic splicing enhancers (ESEs) using SVMs
Background: Exonic splicing enhancers (ESEs) activate nearby splice sites and promote the inclusion (vs. exclusion) of exons in which they reside, while being a binding site for S...
Britta Mersch, Alexander Gepperth, Sándor S...