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NAR
2007
62views more  NAR 2007»
15 years 29 days ago
MolProbity: all-atom contacts and structure validation for proteins and nucleic acids
MolProbity is a general-purpose web server offering quality validation for 3D structures of proteins, nucleic acids and complexes. It provides detailed all-atom contact analysis o...
Ian W. Davis, Andrew Leaver-Fay, Vincent B. Chen, ...
CAV
2009
Springer
215views Hardware» more  CAV 2009»
16 years 2 months ago
Homer: A Higher-Order Observational Equivalence Model checkER
We present HOMER, an observational-equivalence model checker for the 3rd-order fragment of Idealized Algol (IA) augmented with iteration. It works by first translating terms of the...
David Hopkins, C.-H. Luke Ong
BIOINFORMATICS
2008
119views more  BIOINFORMATICS 2008»
15 years 1 months ago
Optimal design of thermally stable proteins
Motivation: For many biotechnological purposes, it is desirable to redesign proteins to be more structurally and functionally stable at higher temperatures. For example, chemical ...
Ryan M. Bannen, Vanitha Suresh, George N. Phillips...
BMCBI
2005
151views more  BMCBI 2005»
15 years 1 months ago
stam - a Bioconductor compliant R package for structured analysis of microarray data
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...
Claudio Lottaz, Rainer Spang
ISMB
2003
15 years 2 months ago
Deriving phylogenetic trees from the similarity analysis of metabolic pathways
Comparative analysis of metabolic pathways in different genomes can give insights into the understanding of evolutionary and organizational relationships among species. This type ...
Maureen Heymans, Ambuj K. Singh