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» Functional site prediction selects correct protein models
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BMCBI
2010
127views more  BMCBI 2010»
14 years 9 months ago
PeptideMine - A webserver for the design of peptides for protein-peptide binding studies derived from protein-protein interactom
Background: Signal transduction events often involve transient, yet specific, interactions between structurally conserved protein domains and polypeptide sequences in target prote...
Khader Shameer, Lalima L. Madan, Shivamurthy Veera...
BIBE
2007
IEEE
167views Bioinformatics» more  BIBE 2007»
15 years 1 months ago
Assessing the Performance of Macromolecular Sequence Classifiers
Machine learning approaches offer some of the most cost-effective approaches to building predictive models (e.g., classifiers) in a broad range of applications in computational bio...
Cornelia Caragea, Jivko Sinapov, Vasant Honavar, D...
BMCBI
2010
113views more  BMCBI 2010»
14 years 9 months ago
Improving performance of mammalian microRNA target prediction
Background: MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA...
Hui Liu, Dong Yue, Yidong Chen, Shou-Jiang Gao, Yu...
NAR
2011
277views Computer Vision» more  NAR 2011»
14 years 17 days ago
The 2011 Nucleic Acids Research Database Issue and the online Molecular Biology Database Collection
The current 18th Database Issue of Nucleic Acids Research features descriptions of 96 new and 83 updated online databases covering various areas of molecular biology. It includes ...
Michael Y. Galperin, Guy Cochrane
BMCBI
2010
97views more  BMCBI 2010»
14 years 9 months ago
Kinome-wide interaction modelling using alignment-based and alignment-independent approaches for kinase description and linear a
Background: Protein kinases play crucial roles in cell growth, differentiation, and apoptosis. Abnormal function of protein kinases can lead to many serious diseases, such as canc...
Maris Lapinsh, Jarl E. S. Wikberg