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» Functional site prediction selects correct protein models
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BMCBI
2006
137views more  BMCBI 2006»
14 years 9 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
BMCBI
2008
128views more  BMCBI 2008»
14 years 9 months ago
Validation of an NSP-based (negative selection pattern) gene family identification strategy
Background: Gene family identification from ESTs can be a valuable resource for analysis of genome evolution but presents unique challenges in organisms for which the entire genom...
Ronald L. Frank, Cyriac Kandoth, Fikret Erç...
BMCBI
2004
115views more  BMCBI 2004»
14 years 9 months ago
An SVD-based comparison of nine whole eukaryotic genomes supports a coelomate rather than ecdysozoan lineage
Background: Eukaryotic whole genome sequences are accumulating at an impressive rate. Effective methods for comparing multiple whole eukaryotic genomes on a large scale are needed...
Gary W. Stuart, Michael W. Berry
BIOINFORMATICS
2006
101views more  BIOINFORMATICS 2006»
14 years 9 months ago
A lock-and-key model for protein-protein interactions
Motivation: Protein-protein interaction networks are one of the major post-genomic data sources available to molecular biologists. They provide a comprehensive view of the global ...
Julie L. Morrison, Rainer Breitling, Desmond J. Hi...
ICAC
2005
IEEE
15 years 3 months ago
Model-Driven Placement of Compute Tasks and Data in a Networked Utility
An important problem in resource management for networked resource-sharing systems is the simultaneous allocation of multiple resources to an application. Selfoptimizing systems m...
Piyush Shivam, Adriana Iamnitchi, Aydan R. Yumeref...