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» Functional site prediction selects correct protein models
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NIPS
2008
14 years 11 months ago
Predicting the Geometry of Metal Binding Sites from Protein Sequence
Metal binding is important for the structural and functional characterization of proteins. Previous prediction efforts have only focused on bonding state, i.e. deciding which prot...
Paolo Frasconi, Andrea Passerini
BMCBI
2006
120views more  BMCBI 2006»
14 years 9 months ago
Integrating protein structures and precomputed genealogies in the Magnum database: Examples with cellular retinoid binding prote
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
Michael E. Bradley, Steven A. Benner
BMCBI
2006
103views more  BMCBI 2006»
14 years 9 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
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BMCBI
2010
150views more  BMCBI 2010»
14 years 9 months ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
CANDC
2006
ACM
14 years 9 months ago
Predicting O-glycosylation sites in mammalian proteins by using SVMs
O-glycosylation is one of the most important, frequent and complex post-translational modifications. This modification can activate and affect protein functions. Here, we present ...
Sujun Li, Boshu Liu, Rong Zeng, Yu-Dong Cai, Yixue...