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» Functional topology in a network of protein interactions
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44
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BIOINFORMATICS
2004
43views more  BIOINFORMATICS 2004»
14 years 10 months ago
Functional topology in a network of protein interactions
Natasa Przulj, Dennis A. Wigle, Igor Jurisica
125
Voted
LION
2009
Springer
112views Optimization» more  LION 2009»
15 years 5 months ago
A Graph-Based Semi-supervised Algorithm for Protein Function Prediction from Interaction Maps
Abstract. Protein function prediction represents a fundamental challenge in bioinformatics. The increasing availability of proteomics network data has enabled the development of se...
Valerio Freschi
89
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CSB
2005
IEEE
110views Bioinformatics» more  CSB 2005»
15 years 4 months ago
A Topological Measurement for Weighted Protein Interaction Network
High-throughput methods for detecting protein-protein interactions (PPI) have given researchers an initial global picture of protein interactions on a genomic scale. The usefulnes...
Pengjun Pei, Aidong Zhang
BMCBI
2010
179views more  BMCBI 2010»
14 years 11 months ago
A semi-supervised learning approach to predict synthetic genetic interactions by combining functional and topological properties
Background: Genetic interaction profiles are highly informative and helpful for understanding the functional linkages between genes, and therefore have been extensively exploited ...
Zhuhong You, Zheng Yin, Kyungsook Han, De-Shuang H...
115
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BIBE
2005
IEEE
154views Bioinformatics» more  BIBE 2005»
15 years 4 months ago
Effective Pre-Processing Strategies for Functional Clustering of a Protein-Protein Interactions Network
In this article we present novel preprocessing techniques, based on topological measures of the network, to identify clusters of proteins from Protein-protein interaction (PPI) ne...
Duygu Ucar, Srinivasan Parthasarathy, Sitaram Asur...