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BMCBI
2011
14 years 4 months ago
Investigating the effect of paralogs on microarray gene-set analysis
Background: In order to interpret the results obtained from a microarray experiment, researchers often shift focus from analysis of individual differentially expressed genes to an...
Andre J. Faure, Cathal Seoighe, Nicola J. Mulder
97
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BMCBI
2011
14 years 4 months ago
A quality metric for homology modeling: the H-factor
Background: The analysis of protein structures provides fundamental insight into most biochemical functions and consequently into the cause and possible treatment of diseases. As ...
Eric di Luccio, Patrice Koehl
102
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JNCA
2011
126views more  JNCA 2011»
14 years 4 months ago
Coordinated session-based admission control with statistical learning for multi-tier internet applications
Popular Internet applications deploy a multi-tier architecture, with each tier provisioning a certain functionality to its preceding tier. In this paper, we address the challengin...
Sireesha Muppala, Xiaobo Zhou
PRL
2010
149views more  PRL 2010»
14 years 4 months ago
Adaptive linear models for regression: Improving prediction when population has changed
The general setting of regression analysis is to identify a relationship between a response variable Y and one or several explanatory variables X by using a learning sample. In a ...
Charles Bouveyron, Julien Jacques
BIOINFORMATICS
2011
14 years 1 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...