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» Fundamentals of Generic Programming
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BMCBI
2010
183views more  BMCBI 2010»
14 years 11 months ago
SOPRA: Scaffolding algorithm for paired reads via statistical optimization
Background: High throughput sequencing (HTS) platforms produce gigabases of short read (<100 bp) data per run. While these short reads are adequate for resequencing application...
Adel Dayarian, Todd P. Michael, Anirvan M. Sengupt...
BMCBI
2008
126views more  BMCBI 2008»
14 years 11 months ago
NITPICK: peak identification for mass spectrometry data
Background: The reliable extraction of features from mass spectra is a fundamental step in the automated analysis of proteomic mass spectrometry (MS) experiments. Results: This co...
Bernhard Y. Renard, Marc Kirchner, Hanno Steen, Ju...
BMCBI
2006
133views more  BMCBI 2006»
14 years 11 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...
NC
2008
122views Neural Networks» more  NC 2008»
14 years 11 months ago
Computation with finite stochastic chemical reaction networks
A highly desired part of the synthetic biology toolbox is an embedded chemical microcontroller, capable of autonomously following a logic program specified by a set of instructions...
David Soloveichik, Matthew Cook, Erik Winfree, Jeh...
BMCBI
2005
103views more  BMCBI 2005»
14 years 11 months ago
SeqDoC: rapid SNP and mutation detection by direct comparison of DNA sequence chromatograms
Background: This paper describes SeqDoC, a simple, web-based tool to carry out direct comparison of ABI sequence chromatograms. This allows the rapid identification of single nucl...
Mark L. Crowe