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BMCBI
2010
105views more  BMCBI 2010»
14 years 9 months ago
Evaluation of fecal mRNA reproducibility via a marginal transformed mixture modeling approach
Background: Developing and evaluating new technology that enables researchers to recover gene-expression levels of colonic cells from fecal samples could be key to a non-invasive ...
Nysia I. George, Joanne R. Lupton, Nancy D. Turner...
BMCBI
2010
86views more  BMCBI 2010»
14 years 9 months ago
Fast motif recognition via application of statistical thresholds
Background: Improving the accuracy and efficiency of motif recognition is an important computational challenge that has application to detecting transcription factor binding sites...
Christina Boucher, James King
BMCBI
2007
128views more  BMCBI 2007»
14 years 9 months ago
A Bayesian nonparametric method for prediction in EST analysis
Background: Expressed sequence tags (ESTs) analyses are a fundamental tool for gene identification in organisms. Given a preliminary EST sample from a certain library, several sta...
Antonio Lijoi, Ramsés H. Mena, Igor Prü...
BMCBI
2007
148views more  BMCBI 2007»
14 years 9 months ago
Toward the automated generation of genome-scale metabolic networks in the SEED
Background: Current methods for the automated generation of genome-scale metabolic networks focus on genome annotation and preliminary biochemical reaction network assembly, but d...
Matthew DeJongh, Kevin Formsma, Paul Boillot, John...
BMCBI
2008
104views more  BMCBI 2008»
14 years 9 months ago
ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...