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» GEM System: automatic prototyping of cell-wide metabolic pat...
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97
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BMCBI
2006
145views more  BMCBI 2006»
15 years 9 days ago
GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
Kazuharu Arakawa, Yohei Yamada, Kosaku Shinoda, Yo...
113
Voted
BMCBI
2005
109views more  BMCBI 2005»
15 years 4 days ago
Automation of gene assignments to metabolic pathways using high-throughput expression data
Background: Accurate assignment of genes to pathways is essential in order to understand the functional role of genes and to map the existing pathways in a given genome. Existing ...
Liviu Popescu, Golan Yona
151
Voted
BMCBI
2007
148views more  BMCBI 2007»
15 years 11 days ago
Toward the automated generation of genome-scale metabolic networks in the SEED
Background: Current methods for the automated generation of genome-scale metabolic networks focus on genome annotation and preliminary biochemical reaction network assembly, but d...
Matthew DeJongh, Kevin Formsma, Paul Boillot, John...
120
Voted
BMCBI
2007
165views more  BMCBI 2007»
15 years 7 days ago
Automatic reconstruction of a bacterial regulatory network using Natural Language Processing
Background: Manual curation of biological databases, an expensive and labor-intensive process, is essential for high quality integrated data. In this paper we report the implement...
Carlos Rodríguez Penagos, Heladia Salgado, ...