This paper presents the “Safe-Instantiation Principle,” a new design principle for evaluating extensions of Java with support for generic types. We discuss the GJ and NextGen ...
This paper presents a Model-Based graphical editor for supporting the creation of conceptual models and domain ontologies in a philosophically and cognitively well-founded modeling...
Gene expression signatures from microarray experiments promise to provide important prognostic tools for predicting disease outcome or response to treatment. A number of microarra...
Modularity, hierarchy, and interaction locality are general approaches to reducing the complexity of any large system. A widely used principle in achieving these goals in designin...
Meta-design of socio-technical systems is an approach which complies with the need of integrating two different types of structures and processes: technical systems which are engi...