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77
Voted
ISSTA
2010
ACM
14 years 9 months ago
2010
ACM
Applications that process complex inputs often react in different ways to changes in different regions of the input. Small changes to forgiving regions induce correspondingly smal...
BMCBI
2010
14 years 9 months ago
2010
Background: Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices. This ...
BMCBI
2010
14 years 9 months ago
2010
Background: Phylogenetic relationships between genes are not only of theoretical interest: they enable us to learn about human genes through the experimental work on their relativ...
70
Voted
BMCBI
2010
14 years 9 months ago
2010
Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
BMCBI
2007
2007
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
14 years 9 months ago
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...