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» Gene Expression Data Management: A Case Study
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BMCBI
2010
193views more  BMCBI 2010»
14 years 10 months ago
Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements
Background: Affymetrix GeneChip microarrays are popular platforms for expression profiling in two types of studies: detection of differential expression computed by p-values of t-...
Jakub Mieczkowski, Magdalena E. Tyburczy, Michal D...
BMCBI
2006
132views more  BMCBI 2006»
14 years 9 months ago
Comprehensive quality control utilizing the prehybridization third-dye image leads to accurate gene expression measurements by c
Background: Gene expression profiling using microarrays has become an important genetic tool. Spotted arrays prepared in academic labs have the advantage of low cost and high desi...
Xujing Wang, Shuang Jia, Lisa Meyer, Bixia Xiang, ...
BMCBI
2004
165views more  BMCBI 2004»
14 years 9 months ago
Analysis of oligonucleotide array experiments with repeated measures using mixed models
Background: Two or more factor mixed factorial experiments are becoming increasingly common in microarray data analysis. In this case study, the two factors are presence (Patients...
Hao Li, Constance L. Wood, Thomas V. Getchell, Mar...
HYBRID
2007
Springer
15 years 3 months ago
Switch Detection in Genetic Regulatory Networks
Abstract. This paper considers piecewise affine models of genetic regulatory networks and focuses on the problem of detecting switches among different modes of operation in gene e...
Riccardo Porreca, Giancarlo Ferrari-Trecate, Danie...
ACIIDS
2010
IEEE
170views Database» more  ACIIDS 2010»
14 years 7 months ago
On the Effectiveness of Gene Selection for Microarray Classification Methods
Microarray data usually contains a high level of noisy gene data, the noisy gene data include incorrect, noise and irrelevant genes. Before Microarray data classification takes pla...
Zhongwei Zhang, Jiuyong Li, Hong Hu, Hong Zhou