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» Gene Expression Data Management: A Case Study
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RECOMB
2008
Springer
15 years 10 months ago
Detecting Disease-Specific Dysregulated Pathways Via Analysis of Clinical Expression Profiles
We present a method for identifying connected gene subnetworks significantly enriched for genes that are dysregulated in specimens of a disease. These subnetworks provide a signat...
Igor Ulitsky, Richard M. Karp, Ron Shamir
BMCBI
2007
126views more  BMCBI 2007»
14 years 9 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
BMCBI
2007
169views more  BMCBI 2007»
14 years 9 months ago
Transcription factor target prediction using multiple short expression time series from Arabidopsis thaliana
Background: The central role of transcription factors (TFs) in higher eukaryotes has led to much interest in deciphering transcriptional regulatory interactions. Even in the best ...
Henning Redestig, Daniel Weicht, Joachim Selbig, M...
BMCBI
2006
126views more  BMCBI 2006»
14 years 9 months ago
Differential prioritization between relevance and redundancy in correlation-based feature selection techniques for multiclass ge
Background: Due to the large number of genes in a typical microarray dataset, feature selection looks set to play an important role in reducing noise and computational cost in gen...
Chia Huey Ooi, Madhu Chetty, Shyh Wei Teng
ACSC
2009
IEEE
15 years 4 months ago
Inference of Gene Expression Networks Using Memetic Gene Expression Programming
In this paper we aim to infer a model of genetic networks from time series data of gene expression profiles by using a new gene expression programming algorithm. Gene expression n...
Armita Zarnegar, Peter Vamplew, Andrew Stranieri