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» Gene Expression Data Management: A Case Study
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BMCBI
2008
128views more  BMCBI 2008»
14 years 9 months ago
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate reg
Background: Gene expression measurements from breast cancer (BrCa) tumors are established clinical predictive tools to identify tumor subtypes, identify patients showing poor/good...
David D. Smith, Pål Sætrom, Ola R. Sn&...
BMCBI
2006
86views more  BMCBI 2006»
14 years 9 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
BMCBI
2006
171views more  BMCBI 2006»
14 years 9 months ago
The effect of oligonucleotide microarray data pre-processing on the analysis of patient-cohort studies
Background: Intensity values measured by Affymetrix microarrays have to be both normalized, to be able to compare different microarrays by removing non-biological variation, and s...
Roel G. W. Verhaak, Frank J. T. Staal, Peter J. M....
KDD
2003
ACM
148views Data Mining» more  KDD 2003»
15 years 10 months ago
A highly-usable projected clustering algorithm for gene expression profiles
Projected clustering has become a hot research topic due to its ability to cluster high-dimensional data. However, most existing projected clustering algorithms depend on some cri...
Kevin Y. Yip, David W. Cheung, Michael K. Ng
BMCBI
2008
167views more  BMCBI 2008»
14 years 9 months ago
Not proper ROC curves as new tool for the analysis of differentially expressed genes in microarray experiments
Background: Most microarray experiments are carried out with the purpose of identifying genes whose expression varies in relation with specific conditions or in response to enviro...
Stefano Parodi, Vito Pistoia, Marco Muselli