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» Gene Maps Linearization Using Genomic Rearrangement Distance...
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BMCBI
2007
162views more  BMCBI 2007»
14 years 9 months ago
Three-Dimensional Phylogeny Explorer: Distinguishing paralogs, lateral transfer, and violation of "molecular clock" assumption w
Background: Construction and interpretation of phylogenetic trees has been a major research topic for understanding the evolution of genes. Increases in sequence data and complexi...
Namshin Kim, Christopher Lee
BMCBI
2008
186views more  BMCBI 2008»
14 years 9 months ago
Variable selection for large p small n regression models with incomplete data: Mapping QTL with epistases
Background: Identifying quantitative trait loci (QTL) for both additive and epistatic effects raises the statistical issue of selecting variables from a large number of candidates...
Min Zhang, Dabao Zhang, Martin T. Wells
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BMCBI
2006
95views more  BMCBI 2006»
14 years 9 months ago
Estimate haplotype frequencies in pedigrees
Background: Haplotype analysis has gained increasing attention in the context of association studies of disease genes and drug responsivities over the last years. The potential us...
Qiangfeng Zhang, YuZhong Zhao, Guoliang Chen, Yun ...
BMCBI
2005
120views more  BMCBI 2005»
14 years 9 months ago
SpectralNET - an application for spectral graph analysis and visualization
Background: Graph theory provides a computational framework for modeling a variety of datasets including those emerging from genomics, proteomics, and chemical genetics. Networks ...
Joshua J. Forman, Paul A. Clemons, Stuart L. Schre...
RECOMB
2007
Springer
15 years 10 months ago
A Bayesian Model That Links Microarray mRNA Measurements to Mass Spectrometry Protein Measurements
Abstract. An important problem in biology is to understand correspondences between mRNA microarray levels and mass spectrometry peptide counts. Recently, a compendium of mRNA expre...
Anitha Kannan, Andrew Emili, Brendan J. Frey