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BMCBI
2007
159views more  BMCBI 2007»
14 years 9 months ago
Computational genes: a tool for molecular diagnosis and therapy of aberrant mutational phenotype
Background: A finite state machine manipulating information-carrying DNA strands can be used to perform autonomous molecular-scale computations at the cellular level. Results: We ...
Israel Mark Martínez-Pérez, Gong Zha...
BMCBI
2008
158views more  BMCBI 2008»
14 years 10 months ago
Metrics for GO based protein semantic similarity: a systematic evaluation
Background: Several semantic similarity measures have been applied to gene products annotated with Gene Ontology terms, providing a basis for their functional comparison. However,...
Catia Pesquita, Daniel Faria, Hugo P. Bastos, Ant&...
NAR
2011
253views Computer Vision» more  NAR 2011»
14 years 19 days ago
tRNADB-CE 2011: tRNA gene database curated manually by experts
We updated the tRNADB-CE by analyzing 939 complete and 1301 draft genomes of prokaryotes and eukaryotes, 171 complete virus genomes, 121 complete chloroplast genomes and approxima...
Takashi Abe, Toshimichi Ikemura, Junichi Sugahara,...
BMCBI
2011
14 years 4 months ago
RedundancyMiner: De-replication of redundant GO categories in microarray and proteomics analysis
Background: The Gene Ontology (GO) Consortium organizes genes into hierarchical categories based on biological process, molecular function and subcellular localization. Tools such...
Barry Zeeberg, Hongfang Liu, Ari B. Kahn, Martin E...
CGF
2010
146views more  CGF 2010»
14 years 10 months ago
Pathline: A Tool For Comparative Functional Genomics
Biologists pioneering the new field of comparative functional genomics attempt to infer the mechanisms of gene regulation by looking for similarities and differences of gene activ...
Miriah D. Meyer, Bang Wong, Mark P. Styczynski, Ta...