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FMCAD
2007
Springer
15 years 8 months ago
Analyzing Gene Relationships for Down Syndrome with Labeled Transition Graphs
Abstract— The relationship between changes in gene expression and physical characteristics associated with Down syndrome is not well understood. Chromosome 21 genes interact with...
Neha Rungta, Hyrum Carroll, Eric G. Mercer, Randal...
BMCBI
2005
124views more  BMCBI 2005»
15 years 1 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2004
146views more  BMCBI 2004»
15 years 1 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
116
Voted
BMCBI
2010
181views more  BMCBI 2010»
15 years 2 months ago
Intensity dependent estimation of noise in microarrays improves detection of differentially expressed genes
Background: In many microarray experiments, analysis is severely hindered by a major difficulty: the small number of samples for which expression data has been measured. When one ...
Amit Zeisel, Amnon Amir, Wolfgang J. Köstler,...
180
Voted
RECOMB
2002
Springer
16 years 2 months ago
Discovering local structure in gene expression data: the order-preserving submatrix problem
This paper concerns the discovery of patterns in gene expression matrices, in which each element gives the expression level of a given gene in a given experiment. Most existing me...
Amir Ben-Dor, Benny Chor, Richard M. Karp, Zohar Y...