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BMCBI
2007
113views more  BMCBI 2007»
15 years 2 months ago
CoryneRegNet 4.0 - A reference database for corynebacterial gene regulatory networks
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...
Jan Baumbach
BMCBI
2010
189views more  BMCBI 2010»
15 years 8 days ago
solQTL: a tool for QTL analysis, visualization and linking to genomes at SGN database
Background: A common approach to understanding the genetic basis of complex traits is through identification of associated quantitative trait loci (QTL). Fine mapping QTLs require...
Isaak Y. Tecle, Naama Menda, Robert M. Buels, Esth...
BMCBI
2006
109views more  BMCBI 2006»
15 years 2 months ago
GPNN: Power studies and applications of a neural network method for detecting gene-gene interactions in studies of human disease
Background: The identification and characterization of genes that influence the risk of common, complex multifactorial disease primarily through interactions with other genes and ...
Alison A. Motsinger, Stephen L. Lee, George Mellic...
BMCBI
2011
14 years 5 months ago
Cell Subset Prediction for Blood Genomic Studies
Background: Genome-wide transcriptional profiling of patient blood samples offers a powerful tool to investigate underlying disease mechanisms and personalized treatment decisions...
Christopher R. Bolen, Mohamed Uduman, Steven H. Kl...
BMCBI
2007
122views more  BMCBI 2007»
15 years 1 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...