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» Gene finding in the chicken genome
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BIBM
2008
IEEE
137views Bioinformatics» more  BIBM 2008»
15 years 4 months ago
Exploring Alternative Splicing Features Using Support Vector Machines
Alternative splicing is a mechanism for generating different gene transcripts (called isoforms) from the same genomic sequence. Finding alternative splicing events experimentally ...
Jing Xia, Doina Caragea, Susan Brown
AAIM
2010
Springer
181views Algorithms» more  AAIM 2010»
15 years 25 days ago
Efficient Exact and Approximate Algorithms for the Complement of Maximal Strip Recovery
Given two genomic maps G and H represented by a sequence of n gene markers, a strip (syntenic block) is a sequence of distinct markers of length at least two which appear as subseq...
Binhai Zhu
BMCBI
2010
146views more  BMCBI 2010»
14 years 9 months ago
Revealing and avoiding bias in semantic similarity scores for protein pairs
Background: Semantic similarity scores for protein pairs are widely applied in functional genomic researches for finding functional clusters of proteins, predicting protein functi...
Jing Wang 0004, Xianxiao Zhou, Jing Zhu, Chenggui ...
BMCBI
2007
233views more  BMCBI 2007»
14 years 9 months ago
160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
Isaac T. S. Li, Warren Shum, Kevin Truong
ISMB
2004
14 years 11 months ago
Exploiting conserved structure for faster annotation of non-coding RNAs without loss of accuracy
Motivation: Non-coding RNAs (ncRNAs)--functional RNA molecules not coding for proteins--are grouped into hundreds of families of homologs. To find new members of an ncRNA gene fam...
Zasha Weinberg, Walter L. Ruzzo