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BIBE
2004
IEEE
179views Bioinformatics» more  BIBE 2004»
15 years 1 months ago
Incorporating Ontology-Driven Similarity Knowledge into Functional Genomics: An Exploratory Study
This research explores the feasibility of semantic similarity approaches to supporting predictive tasks in functional genomics. It aims to establish potential relationships betwee...
Francisco Azuaje, Olivier Bodenreider
BMCBI
2004
124views more  BMCBI 2004»
14 years 9 months ago
Tests for finding complex patterns of differential expression in cancers: towards individualized medicine
Background: Microarray studies in cancer compare expression levels between two or more sample groups on thousands of genes. Data analysis follows a population-level approach (e.g....
James Lyons-Weiler, Satish Patel, Michael J. Becic...
BMCBI
2005
122views more  BMCBI 2005»
14 years 9 months ago
Finding genomic ontology terms in text using evidence content
Background: The development of text mining systems that annotate biological entities with their properties using scientific literature is an important recent research topic. These...
Francisco M. Couto, Mário J. Silva, Pedro C...
RECOMB
2008
Springer
15 years 9 months ago
Limitations of Pseudogenes in Identifying Gene Losses
The loss of previously established genes has been proposed as a major force in evolutionary change. While the sequencing of many new species offers the opportunity to identify case...
James C. Costello, Mira V. Han, Matthew W. Hahn
BMCBI
2010
124views more  BMCBI 2010»
14 years 9 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...