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» Gene function prediction using labeled and unlabeled data
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81
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BIBM
2008
IEEE
175views Bioinformatics» more  BIBM 2008»
15 years 4 months ago
Integrative Protein Function Transfer Using Factor Graphs and Heterogeneous Data Sources
We propose a novel approach for predicting protein functions of an organism by coupling sequence homology and PPI data between two (or more) species with multifunctional Gene Onto...
Antonina Mitrofanova, Vladimir Pavlovic, Bud Mishr...
BMCBI
2008
138views more  BMCBI 2008»
14 years 10 months ago
Systematic identification of yeast cell cycle transcription factors using multiple data sources
Background: Eukaryotic cell cycle is a complex process and is precisely regulated at many levels. Many genes specific to the cell cycle are regulated transcriptionally and are exp...
Wei-Sheng Wu, Wen-Hsiung Li
95
Voted
BMCBI
2010
125views more  BMCBI 2010»
14 years 5 months ago
ProbFAST: Probabilistic Functional Analysis System Tool
Background: The post-genomic era has brought new challenges regarding the understanding of the organization and function of the human genome. Many of these challenges are centered...
Israel T. da Silva, Ricardo Z. N. Vêncio, Th...
BIBM
2008
IEEE
142views Bioinformatics» more  BIBM 2008»
15 years 4 months ago
Using Global Sequence Similarity to Enhance Biological Sequence Labeling
Identifying functionally important sites from biological sequences, formulated as a biological sequence labeling problem, has broad applications ranging from rational drug design ...
Cornelia Caragea, Jivko Sinapov, Drena Dobbs, Vasa...
EVOW
2009
Springer
15 years 2 months ago
A Hierarchical Classification Ant Colony Algorithm for Predicting Gene Ontology Terms
Abstract. This paper proposes a novel Ant Colony Optimisation algorithm for the hierarchical problem of predicting protein functions using the Gene Ontology (GO). The GO structure ...
Fernando E. B. Otero, Alex Alves Freitas, Colin G....