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» Gene functional classification from heterogeneous data
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BMCBI
2007
126views more  BMCBI 2007»
14 years 10 months ago
Including probe-level uncertainty in model-based gene expression clustering
Background: Clustering is an important analysis performed on microarray gene expression data since it groups genes which have similar expression patterns and enables the explorati...
Xuejun Liu, Kevin K. Lin, Bogi Andersen, Magnus Ra...
RECOMB
2004
Springer
15 years 10 months ago
Probabilistic discovery of overlapping cellular processes and their regulation
In this paper, we explore modeling overlapping biological processes. We discuss a probabilistic model of overlapping biological processes, gene membership in those processes, and ...
Alexis Battle, Eran Segal, Daphne Koller
BMCBI
2006
107views more  BMCBI 2006»
14 years 10 months ago
Simplifying gene trees for easier comprehension
Background: In the genomic age, gene trees may contain large amounts of data making them hard to read and understand. Therefore, an automated simplification is important. Results:...
Paul-Ludwig Lott, Marvin Mundry, Christoph Sassenb...
BIBE
2008
IEEE
160views Bioinformatics» more  BIBE 2008»
15 years 4 months ago
Parallel integration of heterogeneous genome-wide data sources
— Heterogeneous genome-wide data sources capture information on various aspects of complex biological systems. For instance, transcriptome, interactome and phenome-level informat...
Derek Greene, Kenneth Bryan, Padraig Cunningham
BMCBI
2010
119views more  BMCBI 2010»
14 years 10 months ago
Functional classification of proteins based on projection of amino acid sequences: application for prediction of protein kinase
Background: The knowledge about proteins with specific interaction capacity to the protein partners is very important for the modeling of cell signaling networks. However, the exp...
Boris Sobolev, Dmitry Filimonov, Alexey Lagunin, A...