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» Gene selection via the BAHSIC family of algorithms
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CIBCB
2006
IEEE
15 years 1 months ago
Efficient Probe Selection in Microarray Design
Abstract-- The DNA microarray technology, originally developed to measure the level of gene expression, had become one of the most widely used tools in genomic study. Microarrays h...
Leszek Gasieniec, Cindy Y. Li, Paul Sant, Prudence...
BMCBI
2008
118views more  BMCBI 2008»
14 years 9 months ago
Inferring transcriptional compensation interactions in yeast via stepwise structure equation modeling
Background: With the abundant information produced by microarray technology, various approaches have been proposed to infer transcriptional regulatory networks. However, few appro...
Grace S. Shieh, Chung-Ming Chen, Ching-Yun Yu, Jui...
BMCBI
2010
132views more  BMCBI 2010»
14 years 9 months ago
Consistency, comprehensiveness, and compatibility of pathway databases
Background: It is necessary to analyze microarray experiments together with biological information to make better biological inferences. We investigate the adequacy of current bio...
Donny Soh, Difeng Dong, Yike Guo, Limsoon Wong
DIS
2010
Springer
14 years 8 months ago
Discovery of Conservation Laws via Matrix Search
Abstract. One of the main goals of Discovery Science is the development and analysis of methods for automatic knowledge discovery in the natural sciences. A central area of natural...
Oliver Schulte, Mark S. Drew
BMCBI
2008
84views more  BMCBI 2008»
14 years 9 months ago
Prediction of specificity-determining residues for small-molecule kinase inhibitors
Background: Designing small-molecule kinase inhibitors with desirable selectivity profiles is a major challenge in drug discovery. A high-throughput screen for inhibitors of a giv...
Daniel R. Caffrey, Elizabeth A. Lunney, Deborah J....