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» Gene set analysis using principal components
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BMCBI
2005
121views more  BMCBI 2005»
15 years 1 months ago
Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data
Background: A critical step in processing oligonucleotide microarray data is combining the information in multiple probes to produce a single number that best captures the express...
Kerby Shedden, Wei Chen, Rork Kuick, Debashis Ghos...
BMCBI
2010
240views more  BMCBI 2010»
15 years 2 months ago
CircuitsDB: a database of mixed microRNA/transcription factor feed-forward regulatory circuits in human and mouse
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
Olivier Friard, Angela Re, Daniela Taverna, Michel...
KDD
2009
ACM
229views Data Mining» more  KDD 2009»
16 years 2 months ago
An association analysis approach to biclustering
The discovery of biclusters, which denote groups of items that show coherent values across a subset of all the transactions in a data set, is an important type of analysis perform...
Gaurav Pandey, Gowtham Atluri, Michael Steinbach, ...
BMCBI
2004
102views more  BMCBI 2004»
15 years 1 months ago
Detection of transposable elements by their compositional bias
Background: Transposable elements (TE) are mobile genetic entities present in nearly all genomes. Previous work has shown that TEs tend to have a different nucleotide composition ...
Olivier Andrieu, Anna-Sophie Fiston, Dominique Anx...
ALGORITHMICA
2006
163views more  ALGORITHMICA 2006»
15 years 1 months ago
Building Large Phylogenetic Trees on Coarse-Grained Parallel Machines
Phylogenetic analysis is an area of computational biology concerned with the reconstruction of evolutionary relationships between organisms, genes, and gene families. Maximum likel...
Thomas M. Keane, Andrew J. Page, Thomas J. Naughto...