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BMCBI
2010
87views more  BMCBI 2010»
14 years 12 months ago
Epigenetic domains found in mouse embryonic stem cells via a hidden Markov model
Background: Epigenetics is an important layer of transcriptional control necessary for cell-type specific gene regulation. Recent studies have shown significant epigenetic pattern...
Jessica L. Larson, Guo-Cheng Yuan
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BMCBI
2010
161views more  BMCBI 2010»
14 years 12 months ago
BPDA - A Bayesian peptide detection algorithm for mass spectrometry
Background: Mass spectrometry (MS) is an essential analytical tool in proteomics. Many existing algorithms for peptide detection are based on isotope template matching and usually...
Youting Sun, Jianqiu Zhang, Ulisses Braga-Neto, Ed...
BMCBI
2008
111views more  BMCBI 2008»
14 years 12 months ago
GENOMEPOP: A program to simulate genomes in populations
Background: There are several situations in population biology research where simulating DNA sequences is useful. Simulation of biological populations under different evolutionary...
Antonio Carvajal-Rodríguez
BMCBI
2007
81views more  BMCBI 2007»
14 years 12 months ago
PADB : Published Association Database
Background: Although molecular pathway information and the International HapMap Project data can help biomedical researchers to investigate the aetiology of complex diseases more ...
Hwanseok Rhee, Jin-Sung Lee
BMCBI
2007
144views more  BMCBI 2007»
14 years 12 months ago
Robust regression for periodicity detection in non-uniformly sampled time-course gene expression data
Background: In practice many biological time series measurements, including gene microarrays, are conducted at time points that seem to be interesting in the biologist's opin...
Miika Ahdesmäki, Harri Lähdesmäki, ...