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BMCBI
2008
159views more  BMCBI 2008»
14 years 12 months ago
Multivariate hierarchical Bayesian model for differential gene expression analysis in microarray experiments
Background: Identification of differentially expressed genes is a typical objective when analyzing gene expression data. Recently, Bayesian hierarchical models have become increas...
Hongya Zhao, Kwok-Leung Chan, Lee-Ming Cheng, Hong...
BMCBI
2008
114views more  BMCBI 2008»
14 years 12 months ago
WSPMaker: a web tool for calculating selection pressure in proteins and domains using window-sliding
Background: In the study of adaptive evolution, it is important to detect the protein coding sites where natural selection is acting. In general, the ratio of the rate of non-syno...
Yong Seok Lee, Tae-Hyung Kim, Tae-Wook Kang, Won-H...
BMCBI
2008
122views more  BMCBI 2008»
14 years 12 months ago
A practical comparison of two K-Means clustering algorithms
Background: Data clustering is a powerful technique for identifying data with similar characteristics, such as genes with similar expression patterns. However, not all implementat...
Gregory A. Wilkin, Xiuzhen Huang
BMCBI
2008
97views more  BMCBI 2008»
14 years 12 months ago
MCM-test: a fuzzy-set-theory-based approach to differential analysis of gene pathways
Background: Gene pathway can be defined as a group of genes that interact with each other to perform some biological processes. Along with the efforts to identify the individual g...
Lily R. Liang, Vinay Mandal, Yi Lu, Deepak Kumar
BMCBI
2008
171views more  BMCBI 2008»
14 years 12 months ago
Comparative analysis of five protein-protein interaction corpora
Background: Growing interest in the application of natural language processing methods to biomedical text has led to an increasing number of corpora and methods targeting protein-...
Sampo Pyysalo, Antti Airola, Juho Heimonen, Jari B...