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104
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BMCBI
2006
14 years 12 months ago
2006
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
101
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BMCBI
2006
14 years 12 months ago
2006
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
BMCBI
2006
14 years 12 months ago
2006
Background: The identification of a consensus RNA motif often consists in finding a conserved secondary structure with minimum free energy in an ensemble of aligned sequences. How...
108
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BMCBI
2006
14 years 12 months ago
2006
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
BMCBI
2006
14 years 12 months ago
2006
Background: Determining whether a gene is differentially expressed in two different samples remains an important statistical problem. Prior work in this area has featured the use ...