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BMCBI
2006
127views more  BMCBI 2006»
14 years 10 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
94
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BMCBI
2006
119views more  BMCBI 2006»
14 years 10 months ago
Evaluation of microarray data normalization procedures using spike-in experiments
Background: Recently, a large number of methods for the analysis of microarray data have been proposed but there are few comparisons of their relative performances. By using so-ca...
Patrik Rydén, Henrik Andersson, Mattias Lan...
BMCBI
2006
117views more  BMCBI 2006»
14 years 10 months ago
A method for estimation of elasticities in metabolic networks using steady state and dynamic metabolomics data and linlog kineti
Background: Dynamic modeling of metabolic reaction networks under in vivo conditions is a crucial step in order to obtain a better understanding of the (dis)functioning of living ...
I. Emrah Nikerel, Wouter A. van Winden, Walter M. ...
96
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BMCBI
2006
128views more  BMCBI 2006»
14 years 10 months ago
Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
71
Voted
BMCBI
2006
133views more  BMCBI 2006»
14 years 10 months ago
Web-based analysis of the mouse transcriptome using Genevestigator
Background: Gene function analysis often requires a complex and laborious sequence of laboratory and computer-based experiments. Choosing an effective experimental design generall...
Oliver Laule, Matthias Hirsch-Hoffmann, Tomas Hruz...