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BMCBI
2007
123views more  BMCBI 2007»
14 years 10 months ago
Normalization and experimental design for ChIP-chip data
Background: Chromatin immunoprecipitation on tiling arrays (ChIP-chip) has been widely used to investigate the DNA binding sites for a variety of proteins on a genome-wide scale. ...
Shouyong Peng, Artyom A. Alekseyenko, Erica Larsch...
BMCBI
2007
109views more  BMCBI 2007»
14 years 10 months ago
Discarding duplicate ditags in LongSAGE analysis may introduce significant error
Background: During gene expression analysis by Serial Analysis of Gene Expression (SAGE), duplicate ditags are routinely removed from the data analysis, because they are suspected...
Jeppe Emmersen, Anna M. Heidenblut, Annabeth Laurs...
92
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BMCBI
2007
123views more  BMCBI 2007»
14 years 10 months ago
Robust clustering in high dimensional data using statistical depths
Background: Mean-based clustering algorithms such as bisecting k-means generally lack robustness. Although componentwise median is a more robust alternative, it can be a poor cent...
Yuanyuan Ding, Xin Dang, Hanxiang Peng, Dawn Wilki...
96
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BMCBI
2007
187views more  BMCBI 2007»
14 years 10 months ago
BioWMS: a web-based Workflow Management System for bioinformatics
Background: An in-silico experiment can be naturally specified as a workflow of activities implementing, in a standardized environment, the process of data and control analysis. A...
Ezio Bartocci, Flavio Corradini, Emanuela Merelli,...
BMCBI
2007
114views more  BMCBI 2007»
14 years 10 months ago
Gene models from ESTs (GeneModelEST): an application on the Solanum lycopersicum genome
Background: The structure annotation of a genome is based either on ab initio methodologies or on similaritiy searches versus molecules that have been already annotated. Ab initio...
Nunzio D'Agostino, Alessandra Traini, Luigi Frusci...