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BMCBI
2004
207views more  BMCBI 2004»
14 years 10 months ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...
BMCBI
2004
154views more  BMCBI 2004»
14 years 10 months ago
Computation of elementary modes: a unifying framework and the new binary approach
Background: Metabolic pathway analysis has been recognized as a central approach to the structural analysis of metabolic networks. The concept of elementary (flux) modes provides ...
Julien Gagneur, Steffen Klamt
BMCBI
2004
119views more  BMCBI 2004»
14 years 10 months ago
Identification of polymorphic tandem repeats by direct comparison of genome sequence from different bacterial strains : a web-ba
Background: Polymorphic tandem repeat typing is a new generic technology which has been proved to be very efficient for bacterial pathogens such as B. anthracis, M. tuberculosis, ...
France Denoeud, Gilles Vergnaud
BMCBI
2004
125views more  BMCBI 2004»
14 years 10 months ago
A functional hierarchical organization of the protein sequence space
Background: It is a major challenge of computational biology to provide a comprehensive functional classification of all known proteins. Most existing methods seek recurrent patte...
Noam Kaplan, Moriah Friedlich, Menachem Fromer, Mi...
BMCBI
2004
166views more  BMCBI 2004»
14 years 10 months ago
Gene prediction using the Self-Organizing Map: automatic generation of multiple gene models
Background: Many current gene prediction methods use only one model to represent proteincoding regions in a genome, and so are less likely to predict the location of genes that ha...
Shaun Mahony, James O. McInerney, Terry J. Smith, ...