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BMCBI
2004
117views more  BMCBI 2004»
14 years 10 months ago
Cancer characterization and feature set extraction by discriminative margin clustering
Background: A central challenge in the molecular diagnosis and treatment of cancer is to define a set of molecular features that, taken together, distinguish a given cancer, or ty...
Kamesh Munagala, Robert Tibshirani, Patrick O. Bro...
BMCBI
2004
92views more  BMCBI 2004»
14 years 10 months ago
BioBuilder as a database development and functional annotation platform for proteins
Background: The explosion in biological information creates the need for databases that are easy to develop, easy to maintain and can be easily manipulated by annotators who are m...
J. Daniel Navarro, Naveen Talreja, Suraj Peri, B. ...
BMCBI
2004
151views more  BMCBI 2004»
14 years 10 months ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
BMCBI
2004
167views more  BMCBI 2004»
14 years 10 months ago
Feature selection for splice site prediction: A new method using EDA-based feature ranking
Background: The identification of relevant biological features in large and complex datasets is an important step towards gaining insight in the processes underlying the data. Oth...
Yvan Saeys, Sven Degroeve, Dirk Aeyels, Pierre Rou...
BMCBI
2004
173views more  BMCBI 2004»
14 years 10 months ago
d-matrix - database exploration, visualization and analysis
Background: Motivated by a biomedical database set up by our group, we aimed to develop a generic database front-end with embedded knowledge discovery and analysis features. A maj...
Dominik Seelow, Raffaello Galli, Siegrun Mebus, Ha...