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BMCBI
2008
171views more  BMCBI 2008»
14 years 10 months ago
A general approach to simultaneous model fitting and variable elimination in response models for biological data with many more
Background: With the advent of high throughput biotechnology data acquisition platforms such as micro arrays, SNP chips and mass spectrometers, data sets with many more variables ...
Harri T. Kiiveri
BMCBI
2007
108views more  BMCBI 2007»
14 years 10 months ago
Design and implementation of a generalized laboratory data model
Background: Investigators in the biological sciences continue to exploit laboratory automation methods and have dramatically increased the rates at which they can generate data. I...
Michael C. Wendl, Scott Smith, Craig S. Pohl, Davi...
BMCBI
2005
87views more  BMCBI 2005»
14 years 10 months ago
Efficient decoding algorithms for generalized hidden Markov model gene finders
Background: The Generalized Hidden Markov Model (GHMM) has proven a useful framework for the task of computational gene prediction in eukaryotic genomes, due to its flexibility an...
William H. Majoros, Mihaela Pertea, Arthur L. Delc...
WILF
2007
Springer
170views Fuzzy Logic» more  WILF 2007»
15 years 4 months ago
Time-Series Alignment by Non-negative Multiple Generalized Canonical Correlation Analysis
Background: Quantitative analysis of differential protein expressions requires to align temporal elution measurements from liquid chromatography coupled to mass spectrometry (LC/M...
Bernd Fischer, Volker Roth, Joachim M. Buhmann
BMCBI
2008
153views more  BMCBI 2008»
14 years 10 months ago
Improved general regression network for protein domain boundary prediction
Background: Protein domains present some of the most useful information that can be used to understand protein structure and functions. Recent research on protein domain boundary ...
Paul D. Yoo, Abdur R. Sikder, Bing Bing Zhou, Albe...