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BMCBI
2008
92views more  BMCBI 2008»
15 years 4 months ago
A semiparametric modeling framework for potential biomarker discovery and the development of metabonomic profiles
Background: The discovery of biomarkers is an important step towards the development of criteria for early diagnosis of disease status. Recently electrospray ionization (ESI) and ...
Samiran Ghosh, David F. Grant, Dipak K. Dey, Denni...
BMCBI
2008
80views more  BMCBI 2008»
15 years 4 months ago
Computational evaluation of TIS annotation for prokaryotic genomes
Background: Accurate annotation of translation initiation sites (TISs) is essential for understanding the translation initiation mechanism. However, the reliability of TIS annotat...
Gang-Qing Hu, Xiaobin Zheng, Li-Ning Ju, Huaiqiu Z...
BMCBI
2008
149views more  BMCBI 2008»
15 years 4 months ago
All-paths graph kernel for protein-protein interaction extraction with evaluation of cross-corpus learning
Background: Automated extraction of protein-protein interactions (PPI) is an important and widely studied task in biomedical text mining. We propose a graph kernel based approach ...
Antti Airola, Sampo Pyysalo, Jari Björne, Tap...
BMCBI
2006
106views more  BMCBI 2006»
15 years 4 months ago
Methodological study of affine transformations of gene expression data with proposed robust non-parametric multi-dimensional nor
Background: Low-level processing and normalization of microarray data are most important steps in microarray analysis, which have profound impact on downstream analysis. Multiple ...
Henrik Bengtsson, Ola Hössjer
BMCBI
2006
116views more  BMCBI 2006»
15 years 4 months ago
HotSwap for bioinformatics: A STRAP tutorial
Background: Bioinformatics applications are now routinely used to analyze large amounts of data. Application development often requires many cycles of optimization, compiling, and...
Christoph Gille, Peter N. Robinson