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BMCBI
2010
178views more  BMCBI 2010»
15 years 4 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
BMCBI
2008
129views more  BMCBI 2008»
15 years 4 months ago
A unified approach to false discovery rate estimation
Background: False discovery rate (FDR) methods play an important role in analyzing highdimensional data. There are two types of FDR, tail area-based FDR and local FDR, as well as ...
Korbinian Strimmer
BMCBI
2007
120views more  BMCBI 2007»
15 years 4 months ago
Quantitative sequence-function relationships in proteins based on gene ontology
Background: The relationship between divergence of amino-acid sequence and divergence of function among homologous proteins is complex. The assumption that homologs share function...
Vineet Sangar, Daniel J. Blankenberg, Naomi Altman...
BMCBI
2005
112views more  BMCBI 2005»
15 years 4 months ago
Web services and workflow management for biological resources
Backgorund: The completion of the Human Genome Project has resulted in large quantities of biological data which are proving difficult to manage and integrate effectively. There i...
Paolo Romano 0001, Domenico Marra, Luciano Milanes...
IMC
2004
ACM
15 years 9 months ago
Availability, usage, and deployment characteristics of the domain name system
The Domain Name System (DNS) is a critical part of the Internet’s infrastructure, and is one of the few examples of a robust, highlyscalable, and operational distributed system....
Jeffrey Pang, James Hendricks, Aditya Akella, Robe...